Error while opening files in SharePoint - Unable to open office files in SharePoint Office client

While working a SharePoint having heavy load got an issue for few users while opening documents/excel sheets/ PowerPoint in office client applications. Files that are stored in SharePoint, while opening files in client application got the following error:

Could not open "http://Servername/Documents/Doc". 

After digging into the issue, found that SharePoint Workspace temp files are stored in Office Cache location which is used for synchronizing as stored in the location below,

"C:\Users\login_user_name\AppData\Local\Microsoft\Office\14.0\OfficeFileCache"

By cleaning the temp files we can fix this issue.